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If you are doing it from windows, try using a free program called Rufus to make the flashdrive. Try the defaults and if it won't boot you might have to try different settings. The other way I know...

PS: To load it onto a USB exactly as Knoppix would have done, you would need to boot that up and then make a 2nd flashdrive with Knoppix's menu option. I think maybe that when Knoppix creates a...

I usually use the live usb maker on antiX in dd mode