Khaled Mardam-Bey is the author of mIRC.

Make a shortcut to the mIRC executable on your HDD.
1. That's assuming that you have a working Windows system
with mIRC installed.
2. Click on Start / Run. Type winesetuptk. Follow the prompts.mIRC
3. Wine will automatically detect the Win32 executable when you
run the mIRC shortcut. Follow the prompts.
4. Adjust the settings to your liking: Managed vs unmanaged windows;
the path to the windows system directory.