Koppix needs to be able to detect and automatically setup MultiHead/Multi Terminal Setups. If a computer has multiple monitors but only one keyboard, it should set it up as multi-head with xinerama, otherwise, if there are multiple monitors and multiple keyboards/mice, it should set it up as multi-terminal and possibly put up a setup that asks which keyboards/mice go with each monitor.

This link http://cambuca.ldhs.cetuc.puc-rio.br/multiuser/ can provide a starting place.