What is the problem exactly? You should be able to boot from cd and install as normal? The only things is that you will need to partition the disk and get both swap and enough space to install Knoppix (around 2G). If you don't have a cd drive but you can get the iso onto the machine, you can boot from the iso as described and install from there, you will still have to have a swap partition and you will also need to arrange your partitions so that you can leave the partition with the iso on it alone during install (so perhaps install to hda1 a 3G partition, have hda2 as a 750M partition with just the iso on it, and then hda3 as the rest of the disk for swap). After you have installed you could use qtparted to remove the extra iso partition and resize the other 2 partitions to take up the space howver you like. If you have an existing OS you want to keep on the drive already space is going to become a real issue! Finally as hard disk space is obviously an issue, you could run knoppix from iso and try using klik to add more software that you need. It has it's pro's (easy to "install" a new version of Knoppix just dl the iso and set up the boot loader, read-only operating system so it can't be messed up) and con's (no real apt, overhead of running from a compressed loop, a very few apps don't work with klik ... yet) but it's relevance here is low disk space requirements (700M instead of 2G for the OS, though of course you can strip the 2G of any unneccessary extra software after you install it).