Hello, I just wanted to post an update.

I just got City of Heroes to work, I am no longer running Knoppix, BUT I am running debian, since knoppix is basically debian, this should still work.

1. Follow the instructions in this link to get the NVidia drivers installed.
http://ubuntuforums.org/archive/index.php/t-21554.html

2. Find a copy of Cedega, it comes in .deb packages, so you can install it through apt-get or kpackage with no problem.

3. Copy your game to the proper folders (some new ones will show up in your home folder)

4. run your game #cedega name-of-game-exe

This is how I got my stuff to work. Make sure you follow all the instructions when installing the Nvidia driver, I forgot to remove GLCore, and spent another couple of hours trying to figure out why it wouldn't work. However, I did find out, instead of editing the XF86Config-4 file, your can run dpkg-reconfigure xserver-xfree86 to add the nvidia driver as your default and to remove the things you need to remove.

I know it's a little late for your lan party, but this should get you running for the next one.