Quote Originally Posted by James419
I have not thied to install Knoppix but have installed Debian Sarge- I need to do some work with the boot as I get a kernel panic on boot up still.

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Many distributions will not easily boot from USB- I have gotten many kernek panic messages trying.
Many distros do not boot from USB easily because your system will attempt to mount the root filesystem before the USB device in which the real root filesystem is located. As the USB device cannot be recognized, the mounting will fail and lead to kernel panic.

See the steps I posted here, the magic is to build the right initrd before your system can boot. http://www.knoppix.net/forum/viewtopic.php?t=20961