Per my previous post, forget the /usr directory _find another mount point_. This could be done, however, you would be remastering the knoppix system on the fly and this distro was never meant to be manipulated this way.

You seem to wish a persistent /home/user directory which see hundreds of posts here for assistance.

You can certainly put executables in your home directory as long as any required libraries are present in your system and the application knows where to find them.