Oh I'd deffinitely call it a problem. But I'm pretty sure this is something that is known about. The only real issue is where certain libs are placed. Probably just a problem for those who are mixing and matching releases (stable, testing, unstable) like Knoppix does.

I'm more concerned with thte fact that Gnome 2 has genuine bugs in it. I can't get it installed on my Knoppix hdinstall for the life of me - packages are broken for the moment.