Persistent /home on flash drive: How to avoid burn-out?

[malaire]

I have set up a peristent /home on a flash drive, but I can foresee a problem: Because the image is updated all the time with cache/temp/conf-files, the flash drive will not last very long with intensive system use. (Typically, 10000 writes are guaranteed.) Is there a (relatively simple) way to have /home on a ramdisk, but reading from an image on boot, and updating that image on shutdown?

I don't know if this helps at all, but Puppy Linux seems to have solved this problem.
You can read more about that from How Puppy works

Still, this might be far too difficult to implement in Knoppix.