One possible solution is to:

1. Save the configuration to your hard drive or thumb drive.

2. Add all the setup steps onto the knoppix.sh

3. Every time when startup the knoppix, use the cheat-code: knoppix myconfig=scan

Provided that you know all your setup steps in command mode.

Check out the FAQ 4 from below:

http://www.knoppix.net/wiki/Network_FAQ

I use this method to setup my wireless connection on boot-up time. The idea is the same to you but you just replace all your setup commands into the knoppix.sh.

Good Luck and have fun.

Rgds,
Chip