I'm not sure if this is a query specifically about running the DVD version but for what it's worth I was running the CD version on a Dell OptiPlex GX1 350MHz with 128MB RAM at the weekend and it worked fine although it stuttered a little when loading certain apps from the CD. I'd be inclined to consider running the CD image from hard disk or possibly even doing a hard disk install if I was using this sort of spec for day to day work. Hope this helps.