If the windows programs you are trying to use are installed in WinXP
you may not get them to work. Each program that I wanted to use
would not run in Knoppix unless I installed it in a Win98 system.

So far I have gotten Agent, Trillian & Sam Spade to work under wine
but I had to install them on a Win98 partition first.

Maybe something about Wine not being able to recurse and find
all the dll's in WinXP.

First, run "winesetup" then try to run the program.