If you create a partition on your hard drive of about 700+MB you can boot from the CD and run from that partition by entering the fopllowing cheatcode at boot

knoppix tohd=/dev/hda1

This copies the cd to the hda1 partition and runs it from there, freeing up the CD drive. After you run this the first time you can change the code to run from the hard drive without re-copying all the data.

knoppix fromhd=/dev/hda1