I don't think so because (as I understand it) the script /etc/init.d/knoppix-hd-autoconfig is only active when you install knoppix onto your HDD. So I think the cause for the problems is another one: On startup knoppix loads the wrong driver for the network card, one that is incompatible with the NIC. A solution would be if the knoppix-developers would modify the hardware-detect-mechanism to use the tulip driver instead of the de4x5 for the NICs that have this chip.
But I'm no Linux expert, so I could be wrong.