I had no problems with the mid november release of Knoppix (Other than disabling pcmcia probing) , but with the 01-01-02 release, the touchpad on my Dell Inspiron 4100 (same HW as a Dell Latitude C610) goes nuts inside X. If I move my finger slowly it will follow ok, but if I start to speed up at all, the mouse will jump all over the screen clicking things at random. Using an external USB Dell/Logitech Optical mouse works fine.l