If it's an NTFS partition, no. There actually has been a rumor that the new 5.0.1 can write to NTFS "in some cases", whatever that means, but I've yet to see any reports that it works or is safe. If you have NTFS partitions I suggest that you read the rescue faq in the wiki and use Knoppix to make backups of what you need, then install fresh.

If it's a FAT partition, yes, if you can find the bad file then you can delete it. See answer #6 for details.