Here is my grub entry:

title Knoppix 6.2 dvd ISO scan ramdisk=32MB
kernel (hd0,2)/knoppix/linux ramdisk_size=100000 initrd=minirt.gz lang=us apm=power-off vga=791 nomce quiet fromhd=/dev/hda3/knoppix bootfrom=/knoppix/*.iso config=scan home=scan ramdisk=32768 noprompt
initrd (hd0,2)/knoppix/minirt.gz
boot

I have linux, minrt.gz and knoppix.iso in hda3

It can boot part way where it seems to be searching for usb and stops with:
could not mount disk to /mnt-system. Starting debugging shell.....

box is amd 3500+ 1gig ram opensuse 11.3